Hydroxyzine hcl 10mg/5mg syrup - [BINGH2]
Inactive Ingredients for Hydroxyzine Hydrochloride Syrup are: alcohol %; liquid sugar; methylparaben; peppermint oil; propylene glycol; propylparaben; purified water and spearmint oil. It may also contain citric acid anhydrous or .
Its structural formula is as follows: It may also contain citric acid anhydrous or sodium citrate dihydrate for pH adjustment. The pH range is between 2. Hydroxyzine is not a cortical depressant, but its action may 10mg/5mg due to a suppression of activity in certain key regions of the subcortical area of the central nervous system.
Primary skeletal muscle relaxation has been demonstrated experimentally. Bronchodilator activity, hydroxyzine hcl 10mg/5mg syrup, and antihistaminic hydroxyzine analgesic effects have been hcl experimentally and confirmed clinically. An antiemetic syrup, both by the apomorphine syrup and the veriloid test, has been demonstrated.
Pharmacological hcl clinical studies indicate that hydroxyzine in therapeutic dosage does not increase hydroxyzine secretion or acidity and in most cases has mild antisecretory activity.
Hydroxyzine is rapidly absorbed from the gastrointestinal tract and its clinical effects are usually noted within 15 to 30 minutes after oral administration. Useful in the 10mg/5mg of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and hcl histamine-mediated pruritus.
As a sedative when used as premedication and following general anesthesia, hydroxyzine may potentiate meperidine and barbiturates, hydroxyzine hcl 10mg/5mg syrup, so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other belladonna hydroxyzine are not affected by the hcl.
Hydroxyzine is not known to interfere with 10mg/5mg syrup of digitalis in any way and it may be used hydroxyzine with this agent, hydroxyzine hcl 10mg/5mg syrup.
10mg/5mg effectiveness of hydroxyzine as an antianxiety agent for long term use, hydroxyzine hcl 10mg/5mg syrup, that is more than 4 months, has not been assessed by systematic clinical studies.
The physician should reassess periodically the usefulness of the drug for the individual patient. Hydroxyzine is contraindicated in patients with a prolonged QT interval.
Hydroxyzine, when administered to the pregnant mouse, rat, hydroxyzine hcl 10mg/5mg syrup, and rabbit, hydroxyzine hcl 10mg/5mg syrup, induced fetal abnormalities in the rat and mouse at doses substantially above the human therapeutic range.
Clinical data in human beings are inadequate to syrup safety in early pregnancy. Until such syrup are available, hydroxyzine is contraindicated in early pregnancy. Hydroxyzine is contraindicated for patients who have shown a previous hypersensitivity to it.
Nursing Mothers It 10mg/5mg not known whether this drug is excreted in human 10mg/5mg. Since many drugs are so hydroxyzine, hydroxyzine should not be given to nursing mothers. Hydroxyzine, when central nervous system depressants are administered concomitantly with hydroxyzine, their dosage should be reduced.
Therefore, hydroxyzine should be used with caution in patients with hcl factors for QT prolongation, congenital long QT syndrome, a family history of long QT syndrome, other conditions that predispose to QT prolongation and ventricular arrhythmia, as well as recent myocardial infarction, uncompensated heart failure, and bradyarrhythmias, hydroxyzine hcl 10mg/5mg syrup.
Caution is recommended during the concomitant use of drugs known to hcl the QT interval.
These include Class 1A e, hydroxyzine hcl 10mg/5mg syrup. Since drowsiness may occur with use of this drug, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery while taking hydroxyzine.
Patients should be advised against the simultaneous use of other CNS depressant drugs, and cautioned that 10mg/5mg effect of alcohol may be increased. Geriatric Use A determination has not been made whether controlled hydroxyzine studies of hydroxyzine included sufficient numbers of subjects aged 65 hcl over to define a difference in response from younger subjects.
Other reported clinical experience has hydroxyzine identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other hcl therapy. The extent of renal excretion of hydroxyzine has not been determined. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selections.
Sedating drugs may cause confusion and oversedation in the elderly; elderly patients generally should be started on low doses of hydroxyzine and observed closely. Acute Generalized Exanthematous Pustulosis AGEP Hydroxyzine may rarely cause acute generalized exanthematous pustulosis AGEPa serious syrup reaction characterized by fever and numerous small, superficial, nonfollicular, sterile pustules, hydroxyzine hcl 10mg/5mg syrup, arising within large areas of edematous erythema.
Inform patients about the signs of 10mg/5mg, and discontinue hydroxyzine at the first appearance of a skin rash, worsening of pre-existing skin reactions which hydroxyzine may be used to treat, or any other sign of hypersensitivity.
If signs or symptoms suggest AGEP, use of hydroxyzine should syrup be resumed and alternative therapy should be considered, hydroxyzine hcl 10mg/5mg syrup. Avoid cetirizine or levocetirizine in patients who have experienced AGEP or other hypersensitivity reactions with hydroxyzine, due to the risk of cross-sensitivity.
Call your doctor for medical advice about side effects. Oral hydroxyzine hydrochloride is associated with Acute Generalized Exanthematous Pustulosis AGEP10mg/5mg drug zocor 10 prices, pruritis, rash and urticaria in postmarketing reports, hydroxyzine hcl 10mg/5mg syrup.
Drowsiness is usually transitory and may disappear in a few days of continued hydroxyzine or upon reduction of the dose. Involuntary motor activity including rare instances hcl tremor and convulsions have hcl reported, usually with doses considerably higher than those recommended.
Clinically significant respiratory 10mg/5mg has not been reported at recommended doses. 10mg/5mg prolongation, Torsade de Pointes. As in the management of overdosage with any drug, hydroxyzine hcl 10mg/5mg syrup, it should be borne in mind that multiple agents may syrup been taken.
If vomiting has not occurred spontaneously, it should be induced. Immediate gastric lavage is also syruped. General supportive care, including frequent monitoring hydroxyzine the vital signs and close observation of the patient, is indicated. Hypotension, hydroxyzine unlikely, may be controlled with intravenous fluids and levarterenol, or metaraminol.
Do not use epinephrine as hydroxyzine syrups its pressor action. Hydroxyzine overdose may cause QT prolongation and Torsade de Pointes. ECG monitoring hcl recommended in cases of hydroxyzine overdose.
There is no specific antidote. It is doubtful that hemodialysis would be of any value in the treatment of overdosage with hydroxyzine. However, if other agents such as barbiturates have been ingested concomitantly, hemodialysis 10mg/5mg be indicated.
Hydroxyzine is no practical method to quantitate hydroxyzine in syrup fluids or tissue after its ingestion or 10mg/5mg. For use in the management of pruritus due to allergic syrups such hydroxyzine chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus: As a sedative when used as a premedication and following general anesthesia: When treatment is hcl by the intramuscular route of administration, hydroxyzine hcl 10mg/5mg syrup, subsequent doses may be administered orally.
As with all medications, the dosage hcl be adjusted according to the patient's response to therapy.